pure Coluracetam powder is a kind of sitan drugs under development, which belongs to sitan derivatives. Cetanes are widely used in the clinical treatment of cognitive dysfunction and epilepsy because of their unique mechanism of action, remarkable curative effect and extremely low toxicity. This variety is still in clinical trial stage in Kalaszi.
Pure Coluracetam Powder can increase the activity of cholinergic neurons and improve cognition by participating in HACU process and increasing the speed-limiting step of choline uptake by synapses to synthesize neurotransmitter acetylcholine.
pure Coluracetam powder | Coluracetam Molecular formula |
Coluracetam enhances high-affinity choline uptake (HACU) which is the rate limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown Pure Coluracetam Powder to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system.
Note: This compound should only be used for research purposes. All compounds have risks. Please consult your doctor and learn about available studies before eating. This product is not used to diagnose, treat, cure or prevent any diseases.
Product Specification
Item |
Specification |
Results |
Description |
White or almost white crystalline powder |
White crystalline powder |
Solubility |
diffluent in Ach, slightly soluble in methanol,almost insoluble in chloroform |
Complies |
HPLC |
Comply with standard |
Complies |
A292/A227 |
2.28~2.42 |
2.36 |
IR |
IR should comply with the reference standard spectrum. |
Complies |
citrate |
positive |
Complies |
Acidity |
3.0~5.0 |
3.63 |
Loss on Drying |
≤1.0% |
0.32% |
Residue on ignition |
≤0.1% |
0.04% |
Heavy Metals |
≤20ppm |
Complies |
Relevant Impurity |
≤0.5% |
0.28% |
Methanol |
≤0.3% |
0.02% |
Methylene dichloride |
≤0.06% |
0.017% |
N,N-Dimethyl formamide |
≤0.088% |
Not detected |
Assay |
98.5~101.5% |
99.6% |
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